В грибах обнаружен "витамин долголетия": его эффекты и научные данные

17.11.2025

Необходимы крупномасштабные продолжительные рандомизированные контролируемые испытания, способные подтвердить причинно-следственную связь между дополнительным приемом эрготионеина и такими клиническими исходами, как частота случаев деменции или сердечно-сосудистых осложнений. (2,7-10)

Ссылки:
1.Beelman, R. B., Kalaras, M. D., Phillips, A. T., and Richie, J. P., Jr. (2020). Is ergothioneine a 'longevity vitamin' limited in the American diet? Journal of Nutritional Science 9. DOI:10.1017/jns.2020.44
2.Wu, L. Y., Kan, C. N., Cheah, I. K., et al. (2022). Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics. Antioxidants 11(9); 1717. DOI:10.3390/antiox11091717
3.Paul, B. D. (2022). Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles? Antioxidants and Redox Signaling 36 (16-18); 1306-1317. DOI:10.1089/ars.2021.0043
4.Fovet, T., Guilhot, C., Delobel, P., et al. (2022). Ergothioneine Improves Aerobic Performance Without Any Negative Effect on Early Muscle Recovery Signaling in Response to Acute Exercise. Frontiers in Physiology 13. DOI:10.3389/fphys.2022.834597
5.Gründemann, D., Hartmann, L., and Flögel, S. (2022). The ergothioneine transporter (ETT): substrates and locations, an inventory. FEBS Letters 596 (10); 1252-1269. DOI:10.1002/1873-3468.14269
6.Cheah, I. K., Tang, R. M. Y., Yew, T. S. Z., et al. (2017). Administration of Pure Ergothioneine to Healthy Human Subjects: Uptake, Metabolism, and Effects on Biomarkers of Oxidative Damage and Inflammation. Antioxidants and Redox Signaling 26 (5); 193-206. DOI:10.1089/ars.2016.6778
7.Uffelman, C. N., Doenges, K. A., Armstrong, M. L., et al. (2023). Metabolomics Profiling of White Button, Crimini, Portabella, Lion's Mane, Maitake, Oyster, and Shiitake Mushrooms Using Untargeted Metabolomics and Targeted Amino Acid Analysis. Foods 12 (16); 2985. DOI:10.3390/foods12162985
8.Gede, A. M. M. I., Gu, Q., Phukhatmuen, P., et al. (2025). Advances and prospects of ergothioneine in the treatment of cognitive frailty. Annals of Medicine 57 (1). DOI:10.1080/07853890.2025.2555742
9.Zajac, I. T., Kakoschke, N., Kuhn-Sherlock, B., and May-Zhang, L. S. (2025). The Effect of Ergothioneine Supplementation on Cognitive Function, Memory, and Sleep in Older Adults with Subjective Memory Complaints: A Randomized Placebo-Controlled Trial. Nutraceuticals 5 (3); 15. DOI:10.3390/nutraceuticals5030015
10.Smith, E., Ottosson, F., Hellstrand, S., et al. (2019). Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart 106 (9); 691-697. DOI:10.1136/heartjnl-2019-315485

Источник: https://www.news-medical.net/health/Ergothioneine-in-Mushrooms-Health-Effects-and-Scientific-Evidence.aspx