L-карнитин: миф о жиросжигании или важнейшая спортивная добавка?

28.12.2017

 
Первоисточники:
Reuter SE, Evans AM. Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects. Clin Pharmacokinet 2012;51:553-72.
Magoulas PL, El-Hattab AW. Systemic primary carnitine deficiency: an overview of clinical manifestations, diagnosis, and management. Orphanet J Rare Dis 2012 Sep 18;7:68(6 pp). doi: 10.1186/1750-1172-7-68.
Brass EP. Carnitine and sports medicine: use or abuse? Ann NY Acad Sci 2004;1033:67-78.
Derosa G, Maffioli P, et al. Effects of combination of sibutramine and L-carnitine compared with sibutramine monotherapy on inflammatory parameters in diabetic patients. Metabolism 2011;60:421-9.
Derosa G, Maffioli P, et al. Orlistat and L-carnitine compared to orlistat alone on insulin resistance in obese diabetic patients. Endocr J 2010;57:777-86.
Vidal-Casariego A, Burgos-Peláez R, et al. Metabolic effects of L-carnitine on type 2 diabetes mellitus: systematic review and meta-analysis. Exp Clin Endocrinol Diabetes 2013;121:234-8.
University of Maryland Medical Center. Carnitine (L-carnitine). https://umm.edu/health/medical/altmed/supplement/carnitine-lcarnitine, accessed August 31, 2015.
Neal EG, Zupec-Kania B, et al. Carnitine, nutritional supplementation and discontinuation of ketogenic diet therapies. Epilepsy Res. 2012 Jul;100(3):267-71.
Leonhardt M, Langhans W. Fatty acid oxidation and control of food intake. Physiol Behav 2004;83:645-51.
Zhang JJ, Wu ZB, et al. L-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled study. Nutr J 2014 Nov 26;13:110(11 pp). doi: 10.1186/1475-2891-13-110.
Guo L, Milburn MV, et al. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health. Proc Natl Acad Sci USA 2015 Aug 17. [Epub, ahead of print]
Huang A, Owen K. Role of supplementary L-carnitine in exercise and exercise recovery. Med Sport Sci 2012;59:135-42.
Stephens FB, Wall BT, et al. Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans. J Physiol 2013;591:4655-66.
Ufnal M, Zadlo A, et al. TMAO: A small molecule of great expectations. Nutrition 2015 Jun 1. [Epub, ahead of print]

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